Can you tell if she can hear? Deafness seems to be associated with biting too hard in a lot of ferrets because they don't get the hint when the other ferrets squeak. Does she bite them too hard? Knowing whether or not she's deaf will be helpful in how you deal with her.
There are certain ferrets that are just wound more tightly than others. Sometimes if you give them more things to do (dig boxes, stuff to run through, chew toys like N-bones, etc) that helps. Usually they calm down by the time they're 6-8 months old, but I've had a number here that took a lot more work.
The best way I've found is to get them addicted to Ferretone (8 in 1 Skin and Coat supplement). They love that stuff. Then you give her a treat when she behaves (for instance, if she runs up to you and puts her foot on your leg, that would get a treat) or does what you want her to do. You'll need to figure out things you want her to do and some different way to get your attention.
You can use a small, empty carrier as "time out" ... if she's being insane and not calming down, put her in the carrier for 5 minutes and let her out. Sometimes just scruffing them and letting them dangle for a few seconds helps to get the message across that you don't like that behavior. Mostly, they learn the quickest via rewards.
Let me know when she bites the most often and see if we can find some common denominator. Only hands? Only ankles? Both? etc.
Oh, and the Bitter Apple should be applied on the ankle or hand you DON'T want her to bite, not into the ferret's mouth like some places tell you.

If she can't taste the Bitter Apple, you'll have to find some Bitter Lime and see if that works.